Downstream processing

Expertise in isolating and purifying high-quality bioproducts for commercial success.

From discovery to industrial scale

We understand the critical role downstream processing plays in the commercial success of biobased materials.

Our expert teams provide comprehensive downstream processing solutions, from initial product isolation through to final purification and formulation, enabling you to deliver high-quality bioproducts rapidly and cost-effectively.

Leveraging our extensive infrastructure and commercially focused expertise, we help you efficiently scale your bioprocesses, ensuring consistent quality and regulatory compliance. 

CPI experts in a lab.
CPI facility.
Two CPI experts operating a facility.

Downstream processing

Expertise in isolating and purifying high-quality bioproducts for commercial success.

From discovery to industrial scale

We understand the critical role downstream processing plays in the commercial success of biobased materials.

Our expert teams provide comprehensive downstream processing solutions, from initial product isolation through to final purification and formulation, enabling you to deliver high-quality bioproducts rapidly and cost-effectively.

Leveraging our extensive infrastructure and commercially focused expertise, we help you efficiently scale your bioprocesses, ensuring consistent quality and regulatory compliance. 

CPI experts in a lab.
Two CPI experts operating a facility.

Downstream processing

Expertise in isolating and purifying high-quality bioproducts for commercial success.

From discovery to industrial scale

We understand the critical role downstream processing plays in the commercial success of biobased materials.

Our expert teams provide comprehensive downstream processing solutions, from initial product isolation through to final purification and formulation, enabling you to deliver high-quality bioproducts rapidly and cost-effectively.

Leveraging our extensive infrastructure and commercially focused expertise, we help you efficiently scale your bioprocesses, ensuring consistent quality and regulatory compliance. 

CPI experts in a lab.
CPI facility.
Two CPI experts operating a facility.

What we offer

Our dedicated downstream processing team provides expertise in isolating and purifying bioproducts, from recombinant proteins to metabolites and fermentation biomass. Our advanced facilities and technologies ensure the highest standards of purity, yield, and performance across multiple scales.

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

Product isolation and recovery

Efficient recovery of your target bioproduct is crucial for commercial viability. We offer a range of tailored techniques to maximise product yield and purity: 

  • High-efficiency centrifugation for effective separation of biomass and product. 

  • Homogenisation processes to improve product recovery and downstream handling. 

  • Filtration technologies, including microfiltration and ultrafiltration, tailored to your product specifications. 

  • Solvent extraction methods optimised for high product purity and yield. 

Advanced purification techniques

Our purification methods deliver superior quality, ensuring your products consistently meet commercial and regulatory requirements: 

  • Affinity chromatography for selective purification of proteins and biomolecules. 

  • Ion-exchange chromatography to separate products based on charge. 

  • Size-exclusion chromatography for separation by molecular size. 

  • Precipitation and crystallisation techniques for product refinement and concentration. 

Formulation development

We help optimise final product formulations to enhance stability, shelf-life, and performance, preparing your products effectively for market. 

  • Tailored formulation strategies for diverse market applications. 

  • Stability and shelf-life optimisation to ensure consistent product performance. 

  • Scalable drying processes including freeze-drying, spray drying, and fluidised bed drying. 

  • Lab-scale testing and pilot formulation trials for accelerated development. 

 

Scale-up and validation

CPI’s specialised scale-up infrastructure and expertise facilitate the transition from laboratory-scale development to robust commercial production, minimising risk and optimising efficiency. 

  • Comprehensive scale-down lab models for accurate process predictions. 

  • Access to pilot and demonstration-scale facilities for industrially-relevant  process validation. 

  • Detailed techno-economic analyses and lifecycle assessments. 

Analytical and regulatory support

Our in-depth analytical capabilities and regulatory expertise streamline your path to commercialisation, ensuring full compliance and high product quality. 

  • Advanced analytical characterisation methods to verify product purity and consistency. 

  • Compliance support including GMP, HACCP, FDA, and other global regulatory standards. 

  • Data generation and regulatory dossier preparation for smooth market entry. 

What we offer

Our dedicated downstream processing team provides expertise in isolating and purifying bioproducts, from recombinant proteins to metabolites and fermentation biomass. Our advanced facilities and technologies ensure the highest standards of purity, yield, and performance across multiple scales.

Product isolation and recovery

Efficient recovery of your target bioproduct is crucial for commercial viability. We offer a range of tailored techniques to maximise product yield and purity: 

  • High-efficiency centrifugation for effective separation of biomass and product. 

  • Homogenisation processes to improve product recovery and downstream handling. 

  • Filtration technologies, including microfiltration and ultrafiltration, tailored to your product specifications. 

  • Solvent extraction methods optimised for high product purity and yield. 

Advanced purification techniques

Our purification methods deliver superior quality, ensuring your products consistently meet commercial and regulatory requirements: 

  • Affinity chromatography for selective purification of proteins and biomolecules. 

  • Ion-exchange chromatography to separate products based on charge. 

  • Size-exclusion chromatography for separation by molecular size. 

  • Precipitation and crystallisation techniques for product refinement and concentration. 

Formulation development

We help optimise final product formulations to enhance stability, shelf-life, and performance, preparing your products effectively for market. 

  • Tailored formulation strategies for diverse market applications. 

  • Stability and shelf-life optimisation to ensure consistent product performance. 

  • Scalable drying processes including freeze-drying, spray drying, and fluidised bed drying. 

  • Lab-scale testing and pilot formulation trials for accelerated development. 

 

Scale-up and validation

CPI’s specialised scale-up infrastructure and expertise facilitate the transition from laboratory-scale development to robust commercial production, minimising risk and optimising efficiency. 

  • Comprehensive scale-down lab models for accurate process predictions. 

  • Access to pilot and demonstration-scale facilities for industrially-relevant  process validation. 

  • Detailed techno-economic analyses and lifecycle assessments. 

Analytical and regulatory support

Our in-depth analytical capabilities and regulatory expertise streamline your path to commercialisation, ensuring full compliance and high product quality. 

  • Advanced analytical characterisation methods to verify product purity and consistency. 

  • Compliance support including GMP, HACCP, FDA, and other global regulatory standards. 

  • Data generation and regulatory dossier preparation for smooth market entry. 

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

What we offer

Our dedicated downstream processing team provides expertise in isolating and purifying bioproducts, from recombinant proteins to metabolites and fermentation biomass. Our advanced facilities and technologies ensure the highest standards of purity, yield, and performance across multiple scales.

Product isolation and recovery

Efficient recovery of your target bioproduct is crucial for commercial viability. We offer a range of tailored techniques to maximise product yield and purity: 

  • High-efficiency centrifugation for effective separation of biomass and product. 

  • Homogenisation processes to improve product recovery and downstream handling. 

  • Filtration technologies, including microfiltration and ultrafiltration, tailored to your product specifications. 

  • Solvent extraction methods optimised for high product purity and yield. 

Advanced purification techniques

Our purification methods deliver superior quality, ensuring your products consistently meet commercial and regulatory requirements: 

  • Affinity chromatography for selective purification of proteins and biomolecules. 

  • Ion-exchange chromatography to separate products based on charge. 

  • Size-exclusion chromatography for separation by molecular size. 

  • Precipitation and crystallisation techniques for product refinement and concentration. 

Formulation development

We help optimise final product formulations to enhance stability, shelf-life, and performance, preparing your products effectively for market. 

  • Tailored formulation strategies for diverse market applications. 

  • Stability and shelf-life optimisation to ensure consistent product performance. 

  • Scalable drying processes including freeze-drying, spray drying, and fluidised bed drying. 

  • Lab-scale testing and pilot formulation trials for accelerated development. 

 

Scale-up and validation

CPI’s specialised scale-up infrastructure and expertise facilitate the transition from laboratory-scale development to robust commercial production, minimising risk and optimising efficiency. 

  • Comprehensive scale-down lab models for accurate process predictions. 

  • Access to pilot and demonstration-scale facilities for industrially-relevant  process validation. 

  • Detailed techno-economic analyses and lifecycle assessments. 

Analytical and regulatory support

Our in-depth analytical capabilities and regulatory expertise streamline your path to commercialisation, ensuring full compliance and high product quality. 

  • Advanced analytical characterisation methods to verify product purity and consistency. 

  • Compliance support including GMP, HACCP, FDA, and other global regulatory standards. 

  • Data generation and regulatory dossier preparation for smooth market entry. 

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

What we offer

Our dedicated downstream processing team provides expertise in isolating and purifying bioproducts, from recombinant proteins to metabolites and fermentation biomass. Our advanced facilities and technologies ensure the highest standards of purity, yield, and performance across multiple scales.

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

Product isolation and recovery

Efficient recovery of your target bioproduct is crucial for commercial viability. We offer a range of tailored techniques to maximise product yield and purity: 

  • High-efficiency centrifugation for effective separation of biomass and product. 

  • Homogenisation processes to improve product recovery and downstream handling. 

  • Filtration technologies, including microfiltration and ultrafiltration, tailored to your product specifications. 

  • Solvent extraction methods optimised for high product purity and yield. 

Advanced purification techniques

Our purification methods deliver superior quality, ensuring your products consistently meet commercial and regulatory requirements: 

  • Affinity chromatography for selective purification of proteins and biomolecules. 

  • Ion-exchange chromatography to separate products based on charge. 

  • Size-exclusion chromatography for separation by molecular size. 

  • Precipitation and crystallisation techniques for product refinement and concentration. 

Formulation development

We help optimise final product formulations to enhance stability, shelf-life, and performance, preparing your products effectively for market. 

  • Tailored formulation strategies for diverse market applications. 

  • Stability and shelf-life optimisation to ensure consistent product performance. 

  • Scalable drying processes including freeze-drying, spray drying, and fluidised bed drying. 

  • Lab-scale testing and pilot formulation trials for accelerated development. 

 

Scale-up and validation

CPI’s specialised scale-up infrastructure and expertise facilitate the transition from laboratory-scale development to robust commercial production, minimising risk and optimising efficiency. 

  • Comprehensive scale-down lab models for accurate process predictions. 

  • Access to pilot and demonstration-scale facilities for industrially-relevant  process validation. 

  • Detailed techno-economic analyses and lifecycle assessments. 

Analytical and regulatory support

Our in-depth analytical capabilities and regulatory expertise streamline your path to commercialisation, ensuring full compliance and high product quality. 

  • Advanced analytical characterisation methods to verify product purity and consistency. 

  • Compliance support including GMP, HACCP, FDA, and other global regulatory standards. 

  • Data generation and regulatory dossier preparation for smooth market entry. 

Downstream processing

applications

We support downstream processing across diverse applications to enhance product purity, quality, and commercial viability.

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Therapeutic proteins and peptides.

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Alternative proteins.

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Nutraceuticals.

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Sustainable chemicals and materials.

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Cosmetic and personal care ingredients.

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Food and beverage ingredients.

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Home care and cleaning solutions.

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Bio-based monomers and polymer.

8-channel pipette and 96-well test plate
8-channel pipette and 96-well test plate
8-channel pipette and 96-well test plate

How we support you

Our specialised infrastructure, dedicated scientists, and commercially focused approach ensure a smooth transition from laboratory-scale development to market-ready bioproducts.

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

Optimise and de-risk your downstream processes 

We guide you through the complexities of downstream processing, optimising yield, purity, and cost-effectiveness. Our team ensures scalable, reproducible processes tailored specifically to your bioproduct requirements, from recombinant proteins and metabolites to biomass and bio-based chemicals. 

Scale with confidence 

Transitioning from laboratory scale to commercial production involves substantial risk. We offer access to pilot and demonstration-scale facilities, helping you validate and refine your downstream processes before significant capital investment. Our comprehensive techno-economic assessments and validation protocols facilitate seamless scaling, ensuring successful commercial production. 

Intellectual property development and protection

We support you in developing and protecting your IP, providing secure environments and expert guidance. By collaborating closely with you, we help develop proprietary downstream processing technologies that maintain your competitive edge. 

Navigate regulatory and commercial hurdles 

We help ensure your downstream processes meet regulatory standards for safety, efficacy, and sustainability. Leveraging extensive regulatory experience across GMP, food-grade certifications (HACCP, FDA), and regulatory dossier submission processes, we simplify your route to market and ensure full compliance. 

Facilitate investment and accelerate innovation 

Securing funding is crucial for scaling downstream processes. Our team assists you in obtaining public and private investment through strategic partnerships, grant applications, and funding opportunities. Collaborating with industry, academia, and government, we provide essential resources, market insights, and investment pathways to accelerate your downstream processing innovations. 

How we support you

Our specialised infrastructure, dedicated scientists, and commercially focused approach ensure a smooth transition from laboratory-scale development to market-ready bioproducts.

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

Optimise and de-risk your downstream processes 

We guide you through the complexities of downstream processing, optimising yield, purity, and cost-effectiveness. Our team ensures scalable, reproducible processes tailored specifically to your bioproduct requirements, from recombinant proteins and metabolites to biomass and bio-based chemicals. 

Scale with confidence 

Transitioning from laboratory scale to commercial production involves substantial risk. We offer access to pilot and demonstration-scale facilities, helping you validate and refine your downstream processes before significant capital investment. Our comprehensive techno-economic assessments and validation protocols facilitate seamless scaling, ensuring successful commercial production. 

Intellectual property development and protection

We support you in developing and protecting your IP, providing secure environments and expert guidance. By collaborating closely with you, we help develop proprietary downstream processing technologies that maintain your competitive edge. 

Navigate regulatory and commercial hurdles 

We help ensure your downstream processes meet regulatory standards for safety, efficacy, and sustainability. Leveraging extensive regulatory experience across GMP, food-grade certifications (HACCP, FDA), and regulatory dossier submission processes, we simplify your route to market and ensure full compliance. 

Facilitate investment and accelerate innovation 

Securing funding is crucial for scaling downstream processes. Our team assists you in obtaining public and private investment through strategic partnerships, grant applications, and funding opportunities. Collaborating with industry, academia, and government, we provide essential resources, market insights, and investment pathways to accelerate your downstream processing innovations. 

How we support you

Our specialised infrastructure, dedicated scientists, and commercially focused approach ensure a smooth transition from laboratory-scale development to market-ready bioproducts.

Optimise and de-risk your downstream processes 

We guide you through the complexities of downstream processing, optimising yield, purity, and cost-effectiveness. Our team ensures scalable, reproducible processes tailored specifically to your bioproduct requirements, from recombinant proteins and metabolites to biomass and bio-based chemicals. 

Scale with confidence 

Transitioning from laboratory scale to commercial production involves substantial risk. We offer access to pilot and demonstration-scale facilities, helping you validate and refine your downstream processes before significant capital investment. Our comprehensive techno-economic assessments and validation protocols facilitate seamless scaling, ensuring successful commercial production. 

Intellectual property development and protection

We support you in developing and protecting your IP, providing secure environments and expert guidance. By collaborating closely with you, we help develop proprietary downstream processing technologies that maintain your competitive edge. 

Navigate regulatory and commercial hurdles 

We help ensure your downstream processes meet regulatory standards for safety, efficacy, and sustainability. Leveraging extensive regulatory experience across GMP, food-grade certifications (HACCP, FDA), and regulatory dossier submission processes, we simplify your route to market and ensure full compliance. 

Facilitate investment and accelerate innovation 

Securing funding is crucial for scaling downstream processes. Our team assists you in obtaining public and private investment through strategic partnerships, grant applications, and funding opportunities. Collaborating with industry, academia, and government, we provide essential resources, market insights, and investment pathways to accelerate your downstream processing innovations. 

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

How we support you

Our specialised infrastructure, dedicated scientists, and commercially focused approach ensure a smooth transition from laboratory-scale development to market-ready bioproducts.

Optimise and de-risk your downstream processes 

We guide you through the complexities of downstream processing, optimising yield, purity, and cost-effectiveness. Our team ensures scalable, reproducible processes tailored specifically to your bioproduct requirements, from recombinant proteins and metabolites to biomass and bio-based chemicals. 

Scale with confidence 

Transitioning from laboratory scale to commercial production involves substantial risk. We offer access to pilot and demonstration-scale facilities, helping you validate and refine your downstream processes before significant capital investment. Our comprehensive techno-economic assessments and validation protocols facilitate seamless scaling, ensuring successful commercial production. 

Intellectual property development and protection

We support you in developing and protecting your IP, providing secure environments and expert guidance. By collaborating closely with you, we help develop proprietary downstream processing technologies that maintain your competitive edge. 

Navigate regulatory and commercial hurdles 

We help ensure your downstream processes meet regulatory standards for safety, efficacy, and sustainability. Leveraging extensive regulatory experience across GMP, food-grade certifications (HACCP, FDA), and regulatory dossier submission processes, we simplify your route to market and ensure full compliance. 

Facilitate investment and accelerate innovation 

Securing funding is crucial for scaling downstream processes. Our team assists you in obtaining public and private investment through strategic partnerships, grant applications, and funding opportunities. Collaborating with industry, academia, and government, we provide essential resources, market insights, and investment pathways to accelerate your downstream processing innovations. 

Can't find what you're looking for?

With over 500 experts we are here to help.

500+

We are over 500 world-class innovation experts, scientists and engineers.

We are over 500 world-class innovation experts, scientists and engineers.

We are over 500 world-class innovation experts, scientists and engineers.

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£3 billion of private investment unlocked

R&D projects delivered

Years of experience

Business collaborations

m² of facilities

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Over £220m of innovation assets

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£3 billion of private investment unlocked

R&D projects delivered

Years of experience

Business collaborations

m² of facilities

Icon Name
Icon Name
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Over £220m of innovation assets

Icon Name

£3 billion of private investment unlocked

R&D projects delivered

Years of experience

Business collaborations

m² of facilities

Icon Name
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Over £220m of innovation assets

Trusted by leading organisations

By working with CPI’s unique combination of in-house expertise and capability, we have saved many months of process development and scale-up, accelerating the commercialisation of our product.

Steve Pearson

Chief Operating Officer

,

Azotic

Why choose CPI?

Work with us to defer capital and workforce investments until your product or process is proven at scale.

Advanced purification techniques

Comprehensive solutions from centrifugation to chromatography.

Precision product recovery

Tailored methods ensuring optimal purity and performance.

Flexible scalability

Robust infrastructure from laboratory to demonstration scale.

Drying expertise

Custom drying solutions for enhanced product stability and shelf life.

Analytical excellence

In-depth characterisation supporting quality assurance and compliance.

Regulatory and IP protection

Detailed regulatory assistance and strong IP development support.

Get in touch

Let's innovate together

At CPI, we understand that every innovation, manufacturing process, and application is unique. Our flexible engagement model builds custom projects around your goals.

Jenny Readman

Downstream processing

Business Development

A headshot of Business Development Manager Jenny Readman.

Get in touch

Let's innovate together

At CPI, we understand that every innovation, manufacturing process, and application is unique. Our flexible engagement model builds custom projects around your goals.

Jenny Readman

Downstream processing

Business Development

A headshot of Business Development Manager Jenny Readman.

Get in touch

Let's innovate together

At CPI, we understand that every innovation, manufacturing process, and application is unique. Our flexible engagement model builds custom projects around your goals.

Jenny Readman

Downstream processing

Business Development

A headshot of Business Development Manager Jenny Readman.